The Shocking Truth About Energy, Fatigue & Chronic Disease – Boost Mitochondrial Power
In this episode of “Hormones, Metabolism, and You,” Dr. Cassie Smith, who specializes in functional medicine endocrinology, teams up with Dr. Bruce Hoffman, an expert in integrative medicine, to delve into the crucial role that mitochondria play in chronic illnesses. They discuss how problems with mitochondria can lead to a range of health issues and stress the importance of getting our mitochondria back in shape.
Dr. Hoffman introduces the idea of the cell danger response and shares practical strategies to boost cellular health. These include making lifestyle changes, adjusting our diets, and being mindful of our environment. The episode highlights a comprehensive approach to healing that considers physical, emotional, and environmental aspects.
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Dr. Bruce Hoffman, MSc, MBchB, FAARM, IFMCP is a Calgary-based Integrative and Functional medicine doctor/practitioner. He is the medical director at the Hoffman Centre for Integrative Medicine and The Brain Treatment Centre of Alberta, specializing in complex medical conditions. He was born in South Africa and obtained his medical degree from the University of Cape Town.
Blog/Transcription:
0:03 welcome back to this week’s episode of Hormones Metabolism and You i’m your host Dr cassie Smith i’m a functional
0:09 medicine endocrinologist based out of Oklahoma City today I am interviewing Dr bruce Hoffman and we had a very
0:17 interesting conversation about mitochondria so if you follow me at all or you know anything about modern
0:23 endocrine you know that we approach health a little differently through this 10 steps to ultimate wellness our very
0:30 first step is mitochondrial health the mitochondria are the powerhouse of your cell they’re responsible for energy
0:37 production is one of the main things although they have about 16 different functions which we talk about in our
0:42 podcast today it’s my belief that if your mitochondria are not functioning
0:48 well or efficiently it is impossible to cure chronic illness and to make you
0:53 feel better because without that ability to produce energy and without that ability of that energy to move from cell
1:00 to cell and allow your cells to function you’re never going to get better and so this is very different than traditional
1:06 medicine but it is a functional medicine approach and so I found a mitochondrial
1:11 expert and I did this with Dr bruce Hoffman so he function he really looks
1:18 at the function of the mitochondria he has years of research he practiced for 30 plus years and he actually has a new
1:25 course out as well which is called the seven stages uh the program of a new
1:30 medical curriculum and we talk about this in the show i’m also going to give you guys a link where you can see a
1:36 webinar he did for 90 minutes about just the mitochondria but what we talked about today was how do you restore a
1:44 cell back to a health cycle so we know that any sort of chronic disease or
1:49 illness there’s a lot of mitochondrial damage or mitochondrial issues with that
1:54 illness and in that person and so he talked about the cell danger response so what happens in your cells when you
2:01 become ill what happens when you have a toxin an outside toxin that enters your body if you have mold what happens when
2:08 you are holding cell phones or seeing blue light or not getting enough sunlight and so we talked about all that
2:14 and he explains at a cellular level what happens to your cell and this is called the cell danger response and then he
2:20 talked about how you restore back cellular health cycle so he talks about
2:25 how there are three cycles of health in a cell and when you activate this cell
2:30 danger response you want the cell when it’s activated to progress through these three stages of you know this health
2:37 cycle so that your cell can restore itself a lot of people get stuck in this stage one of this cell danger response
2:44 and then they have all these inflammatory cytoines that are made bad things start happening and that’s why
2:49 you ultimately get sick so we talked about this we had a very interesting
2:55 conversation about what are some ways that we can restore people back to this
3:00 health cycle with simple things like he focuses on energy he focuses on trauma
3:06 he focuses not only on nutrition but other things and so he was saying that from an energy standpoint he’s very into
3:12 quantum physics from an energy standpoint in your body things like water grounding and light are actually
3:20 more important for your mitochondria than food and so he gave some very just examples that anyone can use about how
3:27 do you ground how do you get the proper light and the proper water so that your body can go back to restoring itself in
3:33 this health cycle we talked a lot about just in general his course and again
3:40 mitochondrial damage and some different things you can do in order to stop this
3:46 and interestingly enough you know I asked him “Wonder if you’re one of the millions or maybe billions of people out
3:52 there who live in cities who live in New York City who live somewhere where you can’t go outside and watch the sun come
3:59 up in the grass every morning.” And so he had a very interesting answer to that
4:04 question that you’ll have to listen to the episode to get but I am super excited for you guys to hear this
4:10 episode and if any of this resonates with you and you’re like “Oh my gosh I know somebody who’s chronically ill i
4:15 know somebody who needs to hear this i know somebody who has tried every medication seen every doctor and things
4:21 haven’t worked and you really want to get to the bottom of chronic illness and understand your mitochondria and
4:26 inflammation and how you get cells to respond and go back to a healthy cell
4:33 cycle then please please please send them this link right now so they can hear this podcast dr bruce
4:40 Hoffman is a Calgarybased integrative and functional medicine
4:46 doctor/practitioner he’s the medical director at the Hoffman Center for Integrative Medicine and the Brain
4:51 Treatment Center of Alberta specializing in complex medical conditions he was
4:57 born in South Africa and obtained his medical degree from the University of Cape Town he has a master’s degree in
5:04 clinical nutrition is a certified functional medicine practitioner is boardcertified with a
5:10 fellowship in anti-aging hormones and regenerative medicine from A4M a
5:16 certified shoemaker mold treatment protocol practitioner certified either
5:22 vdadic practitioner certified family constellation therapist and ILS trained
5:29 in the treatment of limes disease and co- infections so he does all the things you guys he’s co-authored a paper
5:36 published by Dr afron’s group diagnosis of mass cell activation syndrome a
5:42 global consensus in addition to his clinical training Dr hoffman has studied
5:47 with many of the leading mind body and spiritual healers of our times including
5:52 Robert Lowe and John Catbbitson he has shared the stage with
5:58 Dr deepka Chopra and Dr john uh Deatri
6:05 and he continues to spread his inspiring vision of healing and wellness with audiences and patients around the world
6:12 so he is one of the functional medicine like gurus when it comes to just very complex patients as you can see he spent
6:20 his career getting lots of training and so he talks about this in this episode and I cannot wait for you to hear all
6:27 the things that we talk about so let’s dive in so today I have Dr bruce Hoffman
6:33 and I’m very excited to have you thank you for joining us on this episode of Hormones Metabolism and You i want to
6:40 start by having you tell everyone give everyone like a brief five minute or so
6:47 synopsis of I guess how you got here in life your career path and what you do every day so I trained as an MD in Cape
6:56 Town South Africa came to Canada uh did six years as a primary care provider in
7:02 rural Saskatchewan and then started to become curious about what could be done
7:09 to assess and treat complex illness across all the layers and levels of
7:15 experience and so I just became curious and started to investigate multiple
7:21 different modalities of the healing paradigm i did a lot of work with traditional Chinese medicine uh with
7:29 acupuncture herbology ioveetic medicine studied a lot of the mold illness
7:36 criteria did a lot of work on uh family systems and family constellation therapy
7:42 did a lot of work with my cell activation syndrome uh Lyme disease you know all the things that sort of lead to
7:49 a person presenting with chronic complex illness and then over the years I developed a model of how to approach it
7:56 that was broken down into didactic sort of steps and I based it on the ayurveetic
8:03 model of the human experience having layers and levels to it they called
8:09 koshers in ayurveeta and the layers and levels that I use diagnostically and therapeutically and conceptually are the
8:17 first level is the the external environment so everything that comes from the external environment we call
8:23 that the environmental body that then can impact and interact with the dynamic
8:29 physical body which is made up of biochemistry and structure so that’s the
8:34 world that we occupy in traditional medicine and in functional medicine we all people come with symptoms with
8:41 physical issues and physical ailments that’s stage or level two in the model
8:46 and level three in the model is everything to do with physics and electromagnetics that’s to do with the way the sun water
8:54 and magnetism influence the electron transport chain and create the
9:00 ATP which runs everything or the mitochondria sense danger and
9:07 then they go into the shutdown response and create an inflammatory response to the incoming toxins from level one so
9:14 that’s level three is electromagnetics level four is everything to do with
9:20 emotions and trauma which we know is huge in this space right now people who
9:26 have adverse childhood experiences inherited and early
9:31 developmental trauma have a very different HPA axis if you will and a
9:37 diff very different response to uh chronic complex illness they often have
9:43 PTSD symptoms or and very often medical PTSD symptoms because they get told it’s
9:51 all in their head a lot of the time and they often go from pillar to post trying to stabilize and then level five is to
9:58 do with the ego and the intellect and the mind and that has everything to do with the operational sense of self your
10:05 defenses your values your internal dialogue and how you approach the world through your first half of life ego
10:13 sense how you set yourself up through the drives of the first half of life to become somebody in the world then the
10:20 sixth level is to do with the soul i think it’s incredibly important that we
10:25 bring back the soul into the model of working with people and the soul is just
10:31 that part of you that’s below conscious attention you know it’s the personal soul with with all the complexes of
10:38 unresolved emotional issues it’s the family soul the family dynamic you brought into and then it’s the
10:44 mythological or archetypal soul that Jung described in great detail and then
10:50 the seventh level is the spirit body you know transcendent to the personal self is something beyond self and that can be
10:56 explained in many different ways but we can relate to that if we choose to with attention and intention and so I teach
11:03 how to do that so that’s the model I use and when I approach chronic complex
11:08 illness I go through all the layers and levels trying to create a road map for people to follow so that it’s not just
11:15 oh go and see your acupuncturist oh go and do you know neurobi feedback oh go
11:21 to your psychologist or go and take psychedelics i try and structure it in a
11:26 sequenced way for people to approach their complexity with some sense of a
11:31 road map or or order so I now presently consult mostly I did run a big
11:39 clinic for 30 years and I’ve shut that down as of November last year and I just consult and teach online and see
11:46 patients for 3 days of the week uh the rest of the time I’m writing curriculum
11:51 for my teaching so you are very focused on complex medical issues which is why I
11:57 wanted you to come on and talk to people and I know we share a similar belief in the fact that your mitochondria are very
12:04 important for this your mitochondria first and then your gut so I kind of have this 10-step approach that we take
12:10 at Modern Endocrine with people and the first step is dealing with mitochondria and mitochondrial health and so you know
12:17 we were talking before the podcast about mold and some of the chronic illnesses that people have that they’ve had for a
12:23 long period of time and they’ve seen multiple doctors and they’ve never really gotten better and so I want you
12:28 to kind of explain to people you know why you think the mitochondria is so
12:33 important when it comes to anything when it comes to you know just living everyday life chronic illnesses etc and
12:39 then you were telling me about this cell danger response and so I want you to kind of explain to listeners first of
12:45 all what is your mitochondria why is it important and then how this cell danger
12:51 response happens which leads ultimately to illness and diseases does that make sense i’ll do my best
12:59 and we and we can kind of talk back and forth too you don’t have to give us a 30 minute lecture but I that’s kind of the
13:05 basis of of where you start with chronic disease right is the mitochondria not
13:11 necessarily but but generally yes the answer is yes but sometimes you got to
13:18 start with inherited family trauma because it’s so overwhelmingly obvious that they are whatever they experiencing
13:25 has nothing to do with them it’s for something they inherited epigenetically or they may have you know
13:31 mood disorders that are overwhelmingly sort of dominant and you have to go and treat it at a different level before you
13:37 can get to the mitochondrial illness which is at the basis of most chronic illness so if if you so so you’re not
13:44 always approached from a mitochondrial point of view but yes 95 to 99% of all
13:50 chronic diseases that present have mitochondrial heteroplasm or abnormal mutations in
13:57 mitochondrial DNA at the root of their complexity that’s true no question so
14:04 besides mood you said that some of the some things uh you have to look at from a epigenetic standpoint what would it be
14:11 besides like a mood like what sort of traumas are you talking about well family ancestral traumas you know people
14:18 whose parents were murdered in the concentration camp for instance or people who jumped out of the towers in
14:23 911 the children and grandchildren experienced you know symptoms that have
14:29 nothing to do with them they inherited them epigenetically if you look at the work of Rachel um Uhi she’s done all
14:36 this work a formalized education on inherited epigenetic trauma from ancestral influences so sometimes your
14:44 symptoms may have nothing to do with you you may be experiencing what your parents experienced and you’re just
14:50 expressing it without any conscious attachment to this expression that’s epigenetic inheritance of trauma
14:57 so there is something to be said when they say like as a parent if you are chronically stressed or you are
15:04 chronically portraying yourself a certain way to children that can actually affect how children function
15:11 well that’s direct transmission due to direct experience because children are tuned to the mother in the first 10
15:17 years of life somewhat to the father in the second 10 years that’s not epigenetic transfer that’s direct limbic
15:25 resonance with the mother’s own internal dialogue and the way the mother’s in the world if the mother’s offline occupied
15:33 mentally with some other issues maybe the father’s going out and cheating on her her whole attention and preffrontal
15:40 cortex is going to be in an upregulated sympathetic state or in a dorsal veagal shutdown state the child whose
15:48 prefrontal cortex is meant to go into limbic resonance with the mother will
15:54 sense the mother’s offline and the child won’t get the similar um they won’t be
15:59 looked the mother won’t be looking the child in the eye being present with the child the child won’t be finding the
16:06 mother when they look towards the mother’s gaze so the child will then go offline try and meet the security needs
16:12 from the mother by adjusting their personality to to suit the mother’s gaze
16:18 so you go from your authentic self to a provisional self in order to meet the trauma that you’re not you know that’s
16:25 that’s perpetuated by a parental influence that’s not epigenetic that’s
16:30 that’s just pure experiential epigenetic is your your grandfather or your father was murdered
16:38 and you’ve inherited some of the symptomatology of that experience
16:44 yourself and you don’t even know the connection until you look at it so how would you do that you would get
16:50 that from the stress that your parents had you have to do a something called
16:56 family constellation therapy it’s per it was put onto the the uh the basics of
17:03 family constell constellation therapy were um divulged and written up by a man
17:09 by the name of Bert Helinger he’s subsequently died and they’ve been uh
17:14 carried on by another person who’s brilliant at this called Mark Wolan and he wrote a book called It didn’t start
17:20 with you it’s all about you know the symptoms you experience may not have anything to do with you you may have
17:26 inherited them from your ancestors so it’s a whole process it’s
17:31 at my se sixth level of healing it’s looking at family systems at the fourth
17:36 level it’s early developmental experiences that regulate your HPA access and your stress response so
17:44 there’s different layers different levels but but underneath it all the mitochondria are what sense that right
17:52 so the mitochondria too mitochondria’s got 15 20 15 16 functions you know beta
17:58 oxidation proteolyis all sorts of things calcium and influx and so forth but the
18:04 two most dominant um functions of the mitochondria number one is ATP
18:10 production we all know that you know how we through oxidative phosphorilation convert energy from the
18:18 sun and energy from food and by way by just What people don’t know is that the
18:23 food that gets broken down in the electron transport chain through
18:29 oxidative phosphorilation is only about 30% of the incoming signaling what you
18:35 do with expo regards to exposure to the sun and grounding and hydration so sun
18:43 magnetism and water is what determines most of your mitochondrial
18:49 functioning it’s not food it’s mostly how we expose oursel to the outdoor
18:55 environment second to that is what we do by shutting that down the electron
19:00 transport chain by being exposed to non-native
19:06 EMFs cell phones Wi-Fi routers indoor LED lights um computer screens without
19:13 without any sort of software to protect yourself so when you are indoors being
19:19 exposed to non-native EMFs and you’re not basking as a solar panel in the sun
19:25 from morning to night not all day but getting up in the morning with the sun
19:31 grounding during the day and then at night switching off all your overhead lights and your screens and things if
19:37 you’re not following circadium biology and quantum biology principles your mitochondria will be less able to make
19:44 energy ATP you’ll undergo something called mitochondrial hetereropplasm the
19:49 mitochondrial become less efficient at producing energy so that’s the energy production
19:56 part the second s the second most important function of mitochondria is
20:01 the m the mitochondria are sensing they sense toxic load and as soon as they
20:07 sense the toxic load they undergo a huge metabolic transformation so what happens
20:13 is as soon as they sense that the toxic load exceeds their homeostatic
20:21 self-regulation the electron voltage drops the outer membrane of the
20:26 mitochondria under goes a voltage drop oxygen consumption drops but inside the
20:33 cell it goes up where it goes up inside the cell it creates a free radical
20:39 cascade and then you’ll find many metabolic shifts start occurring lipid
20:44 membranes become more rigid sulfur metabolism change methylation defects
20:50 occur amino acid uh transfer becomes impaired you get all these metabolic
20:55 problems that start to happen in an attempt of the mitochondria to take the person away
21:04 from the toxic danger so the cell danger response which is this inflammatory
21:09 response is actually evolutionary there to protect the individual from further
21:14 damage so we as functional medicine practitioners we go and look at all the toxic load mold and heavy metals or
21:23 whatever you wish glyphosate and then we go and do all our metabolic testing we
21:28 do our food sensitivity we do our gut microbiome we do our gut permeability we
21:34 do antibodies to brain peptides we look at you know leaky gut leaky brain leaky
21:40 mitochondria we look at hormones we look at all these those changes in the
21:45 metabolic profile are defensive they’re actually evolutionary there to conserve
21:51 you from further damage so what we in functional medicine did for years is go and fix all those
21:57 pathways but the way you really fix the damage of the cell danger response is by
22:03 restoring the patient back to the health cycle and so Robert Navo’s brilliant work on the cell danger response is a
22:10 must to study when you’re looking at mitochondrial inefficiencies and so most of my clinical work now is not so much
22:18 looking for all the toxins even though I’m trained in you know A4M and AAM and
22:24 IFM and you know the whole cascade we don’t go so much go chase down the toxic
22:29 load we identify the toxic load we identify the metabolic changes that have
22:36 occurred but the primary therapeutic input is on establishing health cycle
22:42 and that’s got about 20 different determinants to it that if the patient’s practicing their metabolic shift occurs
22:50 naturally because the terrain gets established through mitochondrial efficiency and they don’t need to go and
22:56 do so much work because the electron flow is much more efficient and the body starts to produce energy and the body
23:03 starts to heal itself it’s much more in the realm of vitalism you know energy causing health
23:11 as opposed to biochemistry or Newtonian mechanistic medicine which is we got to give lotions
23:17 and potions to turn people around there’s been a shift from level
23:23 two mechanistic biomaccular medicine to physics to energy to sun to water to
23:29 light to the mitochondria because the mitochondria produce energy it’s energy
23:35 10 minutes without energy you’re dead so we know shifting back to a vitalistic concept of medicine as opposed to a
23:42 biochemical model so that’s that’s what I’m doing presently is assisting people
23:50 to establish mitochondrial efficiency and mitochondrial energy production by
23:55 removing the toxic load introducing the the signaling molecules whether they be
24:01 hormones or pep whatever and then establishing the cell the um the um
24:07 health cycle um and really being serious about the health cycle not just paying lip service don’t say oh you need to
24:13 meditate date oh you need to go on a walk oh you need to get sun no you are you getting up at
24:20 sunrise are you outside for 50 60 minutes with this early morning
24:26 sunrise are you going outside an hour a day with your barefoot and grounding are you do you have Iris on
24:33 your computer to stop blue light emissions are you eating a nutrient-dense local seasonal diet that
24:40 provides the right nutrients to your mitochondria because fat’s four times more efficient than carbohydrates in
24:46 producing ATP are you turning off all your lights at night no LED lights are you using
24:54 blue light blocking glasses is your circadian rhythm established and you ask
24:59 people this and you give them handouts on what to do are you hydrating are you doing any cold emotions and cold
25:06 thermogenesis etc etc etc really emphasizing the principles of the health
25:12 cycle before running in and jumping in with you know hormones and peptides and
25:19 exoomes and whatever else you know I have lots of questions Dr hoffman so the
25:25 first question that was a lot of information so I’m sure people listening are their their brains are spinning so
25:32 are you saying that simply going outside grounding in the sun and drinking enough
25:38 water could be enough to heal someone’s mitochondria no I’m not saying that i’m
25:45 saying unless you establish yourself and weave yourself back into the threads of
25:52 nature your chances of turning chronic disease around is diminished so we’ve
25:58 got to really think about what it means to be involved because what we’ve done
26:04 is we’ve shut out the sun it’s all toxic and put on your sunscreens and it’s nonsense it’s absolutely nonsense so you
26:13 know the principles of the health cycle require circadian biology and the
26:19 principles of quantum biology in order to begin to reestablish electron flow
26:25 through the mitochondria and you got to start there before you become heroic and then start
26:31 using all your hormones and your peptides and everything else if you take a patient off the street with chronic
26:38 complex illness and you start throwing hormones and peptides and all the rest of it you won’t have as much success
26:44 than if you ask them to establish themselves in the health cycle principles before they begin the
26:52 signaling molecules robert Nau’s papers is essential in reading he has one
26:57 diagram like this which is like everything here’s your toxic load here’s
27:03 your metabolic shifting here’s your signaling molecules you need to change but here’s the health cycle
27:10 principle here’s what you need to do to to to reestablish your connection to the
27:17 most potent source of healing which is the sun and the earth and the water because you know
27:23 water inside your cell membranes you’ve got you know there’s
27:28 four stages of water this in the fourth stage is this gel-like water called easy
27:33 water which separates into electrons and protons and that’s really that gel-like
27:39 water is what conducts the electrical flow through your mitochondria and if you’re not well hydrated and you don’t
27:45 have adequate easy water you don’t produce ATP or you produce much limited
27:50 ATP so heighten but not just any water it’s like structured water it’s dutarium
27:58 poor dutarium light water it’s there’s a whole whole way that you induce um water
28:07 easy water back into your mitochondrial system these are about 20 things you can do to do that it’s not just drink more
28:13 water it’s not that so I’m sure a lot of people listening to this here’s my question there are millions if not
28:20 billions of people in the world who live somewhere where it’s going to be almost
28:26 impossible to ground themselves especially for an hour right so like if
28:31 you live in New York City if you live in Los Angeles you know if you live in one
28:36 of these places where there’s not really a place to ground what do you do in that
28:42 case or if you live in Oklahoma City where I live but you can’t be outside for 60 minutes when the sun’s coming up
28:48 because you have to be at work then what do you do in these situations so this is a question that’s asked a lot
28:56 and depending on depending on the the mood of the practitioner who answers
29:03 these questions you get different answers if you listen to Jack Cruz have
29:09 you heard of him you want to Jack Cruz is a neurosurgeon who has been probably the
29:16 most vocal and the most advanced in his intellect in terms of advancing physics
29:24 over biochemistry now he’s a neurosurgeon and he’s highly experienced
29:30 and he doesn’t mince words and he’s a trip to listen to
29:36 because when people ask that question he says what do you want me to tell you the first principle of getting a person well
29:43 there’s two things that I’ve noticed over my 30 year 40-year career you don’t
29:49 get better in the same environment that you got sick in and you often don’t get better in the with the same mental field
29:55 that you got sick in in the first place your internal dialogue and the story you tell yourself about who you think you
30:01 are and what’s happened to you is probably not true so the first principle of getting
30:09 well is if you look at my handout on the health cycle number one relocate
30:18 and I’m serious about it jack Cruz get patients from Canada who are in 51 degrees northern latitude no UVB for
30:25 nine months no vitamin D no UVB don’t go outside don’t grown and they phoned them
30:33 with MS and chronic fatigue and fibromyalgia and he just says “Get out of
30:38 Canada.” And they go “But I can’t i got to go to work i got to.” He says “What do you want me to tell you the treatment
30:45 is relocate to where the sun is so you can plug your solar panel back into uh
30:50 the cycles of life so the first answer is relocate the
30:56 second answer is if you can’t relocate from your latitudes to more
31:02 tropics where there’s more sun and magnetism more electrons and magnetism then relocate from inner city to rural
31:10 because if you’re rural there’s less non-native EMFs and then the third is if you can’t do that then you’ve got to
31:17 redesign your home so that your exposure to non-native EMFs is diminished and
31:22 that you need a building biologist for so building biologist is one of the most essential people on your team they come
31:28 in and assess your electrical fields your magnetic fields your radio frequency fields and your dirty
31:34 electricity and they tell you how much you’re being exposed to in the way of these non these nonnative they’re not
31:41 made in nature they’re man-made EMFs and they will then he will then say you need
31:49 to you know turn off your router at night you need to make sure your cell phone is in airplane mode you need to
31:56 turn off the breaker switch behind your bed at night for the two plugs that fire up your um bedside lights uh or you know
32:05 and then you go you need to move your bed away from the fridge that’s behind you in from the kitchen because the
32:10 magnetic field is too intense or you need to get rid of your metal frame bed and get rid of your box springing
32:16 mattress cuz you’re conducting three volts of energy through your body when you sleep at night and it should be less
32:22 than 100 millolts so a building biologist will give you a indications of
32:28 what you need to do to create a sound environment but the first is relocate to
32:35 the to where the tropics are get out of the city or redesign your home those are
32:41 the first three principles where do you find a building biologist is this something you can just Google biology
32:48 building biologist in Oklahoma City do I just Google that buildingbiology.com oh seriously and you
32:55 bring them in and they’re part of your team your dentist is part of your team your nutritionist is part of your team
33:01 your building biologist is part of your team and if you’ve had trauma then you need to work with some of the amygdala
33:07 retraining and somatic experiencing people they become part of your team you need a bit of a team around you when
33:13 you’re approaching chronic complex illness you It’s very difficult to do it alone and the people you work with have
33:19 to be informed about all the possibilities of what you need to turn yourself around it’s complicated
33:27 so let’s say that you do live in Miami or the tropics or somewhere wonderful
33:33 like that you really think that somebody needs to be outside in the sun when it’s
33:38 rising for 60 minutes every day yes so if you look at the if you look at quantum biology and circadian biology
33:45 when you get out when your eyes I’m outside every morning at sunrise 365
33:51 days of the but I do have a hot tub I can sit in if it’s cold but I my hot tub faces the sunrise so you watch the sun
33:58 as the sun rises it starts activating certain receptors in your retino hypothalamic pathways and which then
34:05 activates something called palm c then activates all of these alpha MSH
34:12 and beta MSH and endorphins and neuropeptides and you literally turn on
34:18 your metabolism your hormones your neurotransmitters by sun that’s true you
34:25 just read up all on the circadian biology that’s how it works then so through the eyes no sunglasses no
34:33 contact lenses and if you’ve had cataracts and artificial lenses you’re pretty well screwed because they’re not
34:40 going to get sunlight through there not the rays the the amount of light that you need then you need to sun on your
34:47 skin because melanin melanin on your skin developing a solar callus a suntan
34:54 is what also goes back through the palm pathway to regulate
35:00 neurobiochemistry so skin and then your gut your gut is richly innovated with
35:05 also melanin and palm sea so those are the three areas you need to get sun so you need to get early morning sun to
35:12 kickstart your neuropeptide and hormonal pathways you make melatonin early
35:18 morning sunrise it gets stored and then comes out at night if you have three hours of darkness at night but if you’ve
35:26 got your LED lights on and you’re watching TV and like my patient this morning I saw she’s scrolling through
35:33 she’s scrolling through her cell phone with Bluetooth on cellular data on and
35:38 she’s looking for meditation when she’s being bombarded with non-native frequencies it’s not that’s not what you
35:44 do you know so if you have lenses in your eyes like
35:49 the lenses that they place in your eyes to help you see then you’re never going to get the correct sunlight you’re not
35:54 going to get the right signaling through through the retina hypothalamic pathway back to the palm sea in the hypothalamus
36:01 and pituitary no so then there’s nothing you can do about that so people talk
36:06 about that and they try and some people get the lenses taken out and the eye
36:12 manufact the people who manufacture lenses have been approached by Jack Cruz
36:18 to try and get lenses made that do absorb light and they’ve been
36:23 disinterested to date but he’s still working on it that is interesting okay
36:29 okay so then if you have lenses in your eyes the only thing that people do is get them taken out but then they have
36:35 problems with um accommodation and and so there if you have lenses then there
36:40 would be no reason to go outside and look at the sun coming up no you got your skin still you’re just not going to
36:46 get the eyes you still you can still be early morning sun creates uh infrared
36:52 red and UVA uva rises around 10:00 that actually prepares you for UVB at about
36:58 10 to 12 so UVA actually sets the stage for your so if you have a lot of early
37:04 morning sun on your skin you actually don’t burn as much because the UVA protects you from the UVB later on in
37:11 the day now we don’t recommend you go burn yourself to a frazzle you know because UVB does cause collagen to break
37:17 down and elastin to break down and it will age your skin but you definitely I’ve just lost my I just was in South
37:24 Africa for 2 months i was brown brown brown brown and I’ve been back in Canada at minus 20 for two months and I’m now
37:31 back to my normal color i’m go I can’t wait to get back in the sun so okay so
37:37 those are all very interesting points and so you talked a little bit about this cell danger response and so that so
37:46 basically that’s just your body is so I’m still kind of
37:51 confused about the cell danger response from a perspective of a listener so basically anything that is causing your
37:58 body harm whether it be an infection or you’re not sleeping enough or your
38:05 cortisol is high or you’re stressed or you’re eating processed food or whatever
38:11 you’re worried about paying your bills that will cause the cell danger response
38:16 to occur is that right well those are the triggers of the cell danger response so when the
38:22 mitochondria sense danger and they’ve got to exceed a certain threshold because your mitochondria can have an
38:29 experience of danger 50 60 even 70%
38:34 causing hetropplasmmy malfunctioning but once you cross a certain threshold now
38:40 Doug Wallace is the great mitochondrial researcher with Robert Novo Doug Wallace
38:45 has gone on record saying you can live quite well until you have about 70% of mitochondri ondrial heteroplasm
38:53 dysfunction in any one organ before you start to get symptoms so as soon as you start getting
39:00 symptoms it means the mitochondria in that area have undergone this transition
39:06 from ATP they’ve shut down oxidative phosphorilation they shut down energy
39:12 transfer and they’ve gone into defensive mode and in the defensive mode the key
39:17 triggers are the toxic load creates a huge upregulation of an an of a free
39:24 radical called peroxy nitrate and peroxy nitrate is the final free radical that
39:30 does all the damage it then goes and damages the outer cell membrane the inner cell membrane then goes
39:38 intracellularly and causes destruction of mitochondrial DNA which then unravels
39:44 when mitochondrial DNA unravels it releases ATP from inside the cell to
39:51 outside the cell inside the cell ATP does all the magic outside the cell it’s
39:57 highly inflammatory when it’s outside the cell it then triggers what’s called the
40:03 purinagic halo it creates this huge inflammatory cascade and in
40:09 particular creates mass cell activation syndrome through eight different pathways mass cells are white cells that
40:17 when they sense danger from the external ATP signaling then send out 1,200 other
40:24 inflammatory markers so you go into this chronic inflammatory cycle and then you
40:31 get stuck in there you can get stuck in this chronic inflammatory cycle unless
40:37 you remove the stresses reestablishing signaling
40:43 molecule but don’t attempt it unless you’re practicing all the principles of the health cycle because that is what’s
40:48 going to restore your well-being robert Navo in the cell danger response literature says there’s three phases to
40:56 the cell danger response the first is the chronic inflammatory phase where the
41:02 mitochondria stop communicating they send out all these inflammatory signals and that’s the person who’s sick and if
41:08 it persists they get stuck in it they don’t have a way out the second phase is
41:14 cell danger response two when the cells start to recover and they start to grow
41:19 a little bit and autophagy and autophagy slows down exosomes get secreted
41:26 peptides get secreted and there’s a little bit of harmony that starts to happen cell danger three is
41:34 when peace is restored and the mitochondria start to come back online
41:39 they talk to each other organs start to function again symptoms go down reactivity goes down people feel better
41:46 the brain starts to function so the cell danger response can be stuck and most people are stuck
41:52 usually in cell danger one now SRS chronic inflammatory response syndrome
41:58 which is an innate immune overactivity is a cell danger response
42:03 one condition in each of the different phases there different conditions which
42:09 can be perpetuated by the the health cycle being stuck at that phase so read
42:16 Robert Navio’s work it’s just beautiful it’s so elegant so in surge they’re
42:21 basically stuck in this cell cycle phase one and so they’re not able to like regenerate things or help themselves and
42:28 so that’s where you talk about you need to look at this stress health response or like the stress health cycle and
42:35 figure out how to move them to the next cycle so that they get better that’s what you’re trying to do well you you
42:41 get them established in the health cycle because then the signaling from the light is far more efficient and then
42:47 they can start to generate ATP again but just through lifestyle no fancy
42:53 interventions just lifestyle and if they’re not practicing that their ability to come out of the
42:58 cell danger response is much more difficult now for 25 years I was a functional medicine doctor you know
43:05 using tons of supplements and hormones and and chat not so much anymore not so
43:11 much health cycle dominates we still do hormones we still treat gut permeability we still treat
43:18 but it’s not as hard work you don’t sweat as much it’s easier okay and so this I know
43:28 that you have this new sevenstage program this medical curriculum that
43:33 you’ve made to help train providers and how to I think is that what you’re doing
43:39 is teaching them how to get people into this stress health cycle like correctly or what is the point of this curriculum
43:46 and program that you’ve made well the four major determinants of the program are one is the model that you use to
43:54 assess people must be expanded beyond just physical symptoms toxicology
44:01 physical structure physics electromagnetics brain function autonomic nervous system it’s all level
44:07 three trauma you must be trauma informed because many people come to you with
44:13 high trauma backgrounds and unless you know how to negotiate that you’re going to get stuck then you need to know the mental
44:21 field of an individual you need to know ioveetic doshes you need to know MyersBriggs typology you need to know
44:28 attachment styles you need to know defense structures you need to know how to negotiate all the roadblocks that you
44:35 that you you come up against when you’re treating complexity people will have belief systems that are impenetrable they be
44:42 highly resistant you have to know how to negotiate that with the patient and reestablish some form of vententral
44:48 veagal trust with them because they usually totally distrustful and they they’re angry and they’re sick and they
44:54 feel terrible and going to the traditional people whose pallet is very
45:00 limited it’s just you know N squ D squed name of disease here’s your drug goodbye
45:07 yeah and I think that’s you know unfortunately how doctors are trained now right so unfortunately that’s a
45:13 problem that I’m hoping is going to change but you know traditional traditional medicine that’s how they
45:20 train you right is here’s the disease here’s the prescription it’s not going to change and I don’t really want it to
45:26 change i want doctors to keep being doctors who when they necessary postgraduate if they’re interested shift
45:34 the archetype from doctor as hero and all knowing to doctor as healer that’s a
45:41 very different archetype because the doctor as healer is very aware of the healthy part of the patient and the sick
45:49 part of themselves and so you don’t go as hero you go as in limbic resonance with your patient and you try through
45:56 patient advocacy and your experience with a very expanded pallet of what
46:01 you’ve learned help them negotiate the complexity across all layers and all levels with an expanded road map you try
46:09 and use mitochondrial inefficiency as your starting point you try and work
46:14 through disease and well-being because people once they experience well-being that’s a whole
46:20 different ballgame it’s a whole different relationship that you have with somebody um and so the model I’ve
46:28 developed is trying to create a more experienced practitioner using a much wider pallet in order to interact
46:35 meaningfully with the patients who present and not just doctor as hero
46:40 patient is all sick and then they learn to survive that one-sided relationship which is very disempowering
46:48 no I would completely agree with that i think that you know yeah doctor as hero
46:53 is one thing i think of like surgeons i think of ER doctors i think of I mean you need doctors like that in certain
46:59 circumstances right i mean yeah i mean you know the guy who did the cardiac
47:04 bypass surgery on my dad you know we need that hero like I can’t do that nobody else can do that um you know if
47:11 you get a gunshot wound the surgeon that takes that out and stops your bleeding artery i mean you need that right
47:17 but then most healing I think to your point cuz like I did primary care
47:23 most healing and chronic illnesses in this country need somebody with empathy
47:29 somebody with zero ego and somebody who is willing to sometimes say the things patients don’t want to hear like you
47:35 know to your point like I tell people all the time like in order for me to make you well you have to give up the lifestyle that made you sick are you
47:41 ready to do that and if the answer is no then you’re wasting my time and your money you can go down the street and get
47:46 any doctor in Oklahoma City to write you all the prescriptions you want that’s not what we do at Modern Endocrine right
47:52 like I’m not here to write you prescriptions and I’m not here to tell you what you want to hear i’m here to tell you the truth which is you know
47:58 your lifestyle sucks you’re not sleeping enough you’re being mean to yourself you have some unre you know some trauma you
48:04 need to talk to somebody about i mean all these things and so it it’s true i
48:09 think that people want that out of medicine and that shift is happening which is good but to your point you know
48:15 it’s kind of difficult like right now I’m working on training a couple of providers and it’s really hard because
48:21 you don’t learn any of this in in school and so it takes a to your point a lot of it’s taken me a long time to learn it it
48:27 took you a long time to learn it and so that’s the disfortunate unfortunate I guess thing for patients is that there’s
48:34 not a lot of people who have that mindset currently that’s why it’s a new medical curriculum yeah so you So Dr
48:43 hoffman is helping with that and we’ll make sure that we put all these links in the show not I I appreciate that i think
48:48 that’s amazing you know that’s what we’re working on at Modern Endocrine too i’m almost done with this really good gut curriculum not only for patients i’m
48:55 doing one for patients one for providers because every provider should be talking to their patients about their gut health
49:01 and their diet and their nutrition and but we don’t learn any of that in school you know and I have a million people who
49:06 reach out to me and they’re like “Well how did you learn this?” and I’m like you know like here and there and reading
49:11 papers and just talking to patients and so I’m putting together a curriculum as well for things like that so I
49:17 appreciate you and doing that cuz it is very difficult it’s very complex and to your point I know this cuz I did this
49:24 when I first started doing functional medicine like you said you know at the very beginning it was like oh only
49:30 supplements or only hormones will fix this hormones and supplements don’t fix chronically ill people you’ve got to
49:37 address their gut you’ve got to address their emotional health you’ve got to address their mitochondria you have to
49:42 address trauma like there’s so many things to your point sunlight sleep there’s so many things that you have to
49:48 address um and so it takes time it takes a lot of energy it takes a patient
49:53 that’s really invested too i’m trying to provide the road map based on my
49:59 experience and trainings to so that it’s not as difficult i mean it’s still difficult
50:06 because the the inner and outer experience of the physician and the
50:11 patient relationship is going to be dependent on what the the the inner physician of the healer the knowledge so
50:19 the wisdom and the knowledge of the of the person you’re seeing as oppo and
50:25 then is it in limbic resonance with the patient is there a road map you can follow that shortcircuit some of the
50:31 complexity without using trial and error I’m trying to bring together that road
50:37 map i just did a lecture two days ago for a hour and a half which I’ll make uh
50:44 it’s a webinar I did describing this model in much more detail with PowerPoint slides and if you want to
50:51 make it available to your whoever is interested um I’m sure my staff can provide you with the link so I’ll go
50:58 into detail with PowerPoint on what I’m you know with visuals as to what I’m saying yeah
51:03 okay so I’ll make a note that we’re going to get that link from your assistant and we’ll put it in the show notes so if people want to look at that
51:10 I think that’s very beneficial so I appreciate you kind of diving into this
51:16 different form of functional medicine with me you know I’ve I’ve been very focused on the gut but I do think
51:21 mitochondria is very important and I love a lot of the topics that you bring up and we’ll make sure and put all your
51:28 stuff in the show notes as well as far as your social media i know that you put a put a lot of very interesting and good
51:33 things on social media too so people can actually you know get some ideas of as how they can how they can do this how
51:40 they can fix certain things and ideas of how to get outside more and how to get light into your eyes and and how to grow
51:47 get light on their on their stomach on their stomach okay yeah yeah there’s a
51:52 lot of work being done on the gut microbiome being influenced by melanin but induced by sun on the gut and
51:59 they’ve even developed a lot of you know swimwear which is see-through so the sun will penetrate through the it’ll hide
52:05 your privates but it’ll penetrate and do your paranium and your GI tract at the
52:10 same time there’s a I just let me give a plug for somebody who’s in the space Alexis Jasmine
52:17 she’s she’s uh she’s a quantum biologist in the Jack Cruz model and she’s you
52:22 started out as a gut microbiologist for 20 years I think and now she’s the
52:29 lights been turned on and she’s realizing that the gut microbiome is much better assisted by quantum and
52:35 circadian biology principles than it is through food so she’s worth leading uh
52:41 checking out so let me ask you this when you say light does red light therapy like if you have a medical grade red
52:47 light therapy does that count yes yes okay great so then I do my red light bed I don’t I don’t see the sun every
52:54 morning i just I don’t I’m I’m already working out i’m just I don’t Are you
52:59 working out in the gym i’m working out in the gym blue light not good for you i
53:05 know put your gym outdoors work outdoors watch the sunrise no blue light i’m just
53:11 saying that these things have been I’ll tell my husband we need to put a gym in the backyard um but but I do get in my
53:18 red light bed every day we have a medical grade red light bed at our clinic it’s amazing i love that thing and so I get in that thing for 20
53:25 minutes every day so at least I’m getting that you’re getting that but the sun’s 24’s 12 hours so you’re getting 20
53:32 minutes i do go for walks in the morning and I do go for walks at night after
53:37 dinner but unfortunately I’m stuck in the clinic at least for right now seeing patients i guess we could also just move
53:44 clinic maybe we should just think about moving our clinic outside and doing clinic people do that jack Cruz you see
53:51 him interviewed he’s sitting outside with his shirt off okay with his patients uh he does Zoom calls okay and
53:59 he uses a computer that’s got no blue light uses my patients would think I was insane if I was sitting outside on the
54:05 back patio with my shirt off doing interviews with them that’s We’re not
54:10 call grounding when you walk get yourself shoes with a copper thing on the bottom grounding shoes grounding
54:16 yeah from a clinic called Ryzel r H I not a clinic a website r H I Z A L and
54:23 if you go on to Etsy and you just Google grounding shoes they’re all over the place so if you if it is cold you can
54:29 still use grounding shoes and get benefit okay so I need some copper grounding shoes i’ll I’ll look into all
54:35 of that so thank you for all those tips um I do you know your um your
54:41 significant other actually turned all the blue light off on my phone when I met her in June of last year so I’ve
54:47 never turned it back on so I don’t have the blue light from my phone she like immediately took my phone and was like
54:53 “What are you doing?” and changed all these settings and I actually have Iris on my computer because of her too so I I
54:59 have some blue light blocking um I have my glasses too that she made me get um
55:05 so I I I’m working on it but I will do that so I would like to ask you three
55:12 questions as we kind of wrap up if that’s okay i ask everyone these questions i don’t want you to overthink it but I’m curious as to what you would
55:19 say what is one food that’s most beneficial to your mitochondria and why
55:26 fat protein and fat so any fat well
55:31 saturated fat but you also want you also want essential omega6 and3s this whole no omega6 trend is disastrous don’t
55:38 follow it please it’s wrong you need omega sixes you need omega-3s through fish so fish for omega-3s particularly
55:45 DHA and then protein and fat is those are the foods that fire up the
55:51 mitochondria carbohydrates are poor fuel they’re four times less efficient to produce ATP than fat so fat and protein
56:00 fat and protein okay and it doesn’t matter it can be any fat and protein you’re fine with all of it well no make
56:06 sure that your you know your it must be grass-fed grass-finish you can’t go buy
56:12 you know Safeway meats and things you can’t do that that’s that’s those those are toxic and I know that you’re also
56:18 very big about eating in season too i know that so eating things that are in season yeah okay what is one thing that
56:26 anyone can do and I think I know your answer to this what is one thing that anyone can do that’s 100% free that will
56:32 benefit their health follow Circadium Health Principles they’re all free so just get my hand out and I’ll be willing
56:39 to send it to you oh in the slides if you do get the se if you do get the slideshow I go two pages of the health
56:45 cycle you can just download them follow those all free okay and I’m assuming it’s go outside
56:52 and ground and things like that which are free and then the last question is what is one thing you wish you would
56:58 have known about your health let’s say 30 years ago and that you would have done differently
57:05 I’m speaking to you I’m sure I don’t know how many decades separate us but I
57:10 worked I I’ve gone to 290 conferences and I’ve got 11 different trainings i
57:15 would work from sun up to sun down i go to work in the dark go home in the dark then write write you know protocols and
57:22 look at patient charts for 30 years and then I got an aortic aneurysm that was
57:28 too big and I had to get emergency surgery before it burst and I know that my aortic aneurysm was produced by
57:34 inflammation by being living the lifestyle that I chose to live so that humbled me i shut down my practice i now
57:42 change the way I lead my lifestyle i still do what I love to do which is this but I’m shifting my health priorities
57:49 from education and teaching and running a clinic to my own health practices my
57:57 health my own health cycle principles first and then fulfilling my other destiny which is to keep doing what I’m
58:03 doing so I wish I’d done that 20 years earlier i like that i’m trying to do that myself
58:10 i agree the sun up to sun down is we think we have time we don’t have time we
58:18 sacrifice time for money and career it you you eventually you know Myron Vince
58:25 from Saniv said “Isn’t it amazing and ironic we spend our whole first half of life doing all the things we love to do
58:32 accumulating us you know our our goals in life and accumulating all the money that we want and then we spend the
58:38 second half of life spending all the money we accumulated to fix the health that we neglected no it’s true i I love
58:44 the quote too of you know the busy anyone the busy entrepreneur the busy
58:49 person has a thousand problems and they have all a thousand problems until they have a serious health condition and then
58:55 they have one problem and that’s it you know and it’s so true like raise health
59:00 is your number one value from whatever no matter what your age is you think you’ve got time wait until you get
59:07 something that shuts you down then you realize you sacrificed a lot for time
59:13 yeah no I completely agree i think that that’s all very valuable information so I want to say thank you for all the work
59:20 that you’ve done all the work you’re doing to educate providers and patients is all very important work and thank you
59:26 for your time today we will link all your stuff in the show notes i’ll get the link from the webinar that you did
59:32 so patients can get that and make sure that all your social media is linked as well get it from Maria she knows how to
59:38 link i have no clue how to link anything she’ll do it for you we’ll we’ll take care of you but thank you so much and
59:46 thanks for coming on have a great day okay Cassie see you thanks very much i
59:51 hope that you guys enjoyed this episode of Hormones Metabolism and you i know it was packed full of a lot of things
59:57 sometimes it got a little difficult to follow when we talked about quantum physics but I think there was a lot of really great information to take out of
1:00:04 that and some tips that you can do on a daily basis to help restore your health cycle and make your mitochondria
1:00:11 healthier again like I said if you know anyone who’s dealing with chronic illnesses anyone who struggles with
1:00:16 illnesses who’s seen doctors who has not gotten better who is just sick please please please share this episode with
1:00:22 them that’s why I do this it’s for education i want people to realize there is a route besides traditional medicine
1:00:29 there is a way to heal yourself from a functional standpoint and some of the things we talked about are free and very
1:00:35 easy light therapy grounding drinking water and so just please share this with
1:00:41 anyone who you think it would be beneficial make sure you’re following us anywhere that you get podcast we have
1:00:47 our podcast released every week on Spotify on Apple and on YouTube also
1:00:53 find me on social media i love I’m very active on social media i like to educate so please you know chime in let me know
1:01:00 what you want to learn about let me know who you want me to interview let me know what questions you have and I’m happy to
1:01:05 make content around that lastly please remember that Modern Endocrine is licensed in 39 states and growing we
1:01:13 plan to be in all 50 by the end of 2025 we do virtual visits we are happy to see
1:01:18 you for complex medical conditions we do look at mitochondrial support we also do
1:01:23 a lot of gut health hormones weight loss we do all of it so if you’re interested in becoming a patient check out our
1:01:29 website or we’ll have information in the show notes for that as well thank you so much for joining us this week and for
1:01:36 putting in the time to educate yourself and to try to become a healthier version of yourself i appreciate that and see
1:01:44 you next week [Music] the information presented including any
1:01:49 materials discussed referenced or linked within this podcast are for general educational purposes only not the
1:01:56 practice of medicine no doctor patient relationship is formed from you listening to this podcast or utilizing
1:02:02 any of the information provided i am a doctor but I am not talking to you as your doctor the information provided is
1:02:10 not intended to diagnose or treat health problems or take the place of the professional medical care provided by
1:02:17 your doctor if you are experiencing any health problems including problems you believe have been touched upon in any
1:02:24 respect within this podcast you should consult your doctor about the problems without delay you may ask your doctor
1:02:31 whether he or she believes the information I have provided would be helpful to you but you should still
1:02:36 consult your doctor immediately and follow his or her medical advice as your treating physician i’m just here to
1:02:42 provide you basic knowledge about the issues we discuss so you are more aware of them and can better discuss them with
1:02:49 your doctor that’s why we call it back to the basics join me on the next episode as we continue our journey
1:02:56 [Music]
Disclaimer:
The information presented including any materials discussed, referenced, or linked within this podcast are for general educational purposes only, not the practice of medicine.
No doctor-patient relationship is formed from you listening to this podcast or utilizing any of the information provided.
I am a doctor, but I am not talking to you as your doctor. The information provided is not intended to diagnose or treat health problems or take the place of the professional medical care provided by your doctor.
If you are experiencing any health problems, including problems you believe have been touched upon in any respect within this podcast, you should consult your doctor about the problems without delay. You may ask your doctor whether he or she believes the information I have provided would be helpful to you, but you should still consult your doctor immediately and follow his or her medical advice as your treating physician.
I’m just here to provide you with basic knowledge about the issues we discuss so you are more aware of them and can better discuss them with your doctor.
That’s why we call it Back to the Basics. Join me on the next episode as we continue our journey.